MENT (methylnortestosterone acetate)
Androgenic 650
Anabolic 2300
Chemical Names
19-norandrost-4-en-3-one-17beta-ol
17beta-hydroxy-estr-4-en-3-one
Estrogenic Activity low
Progestational Activity moderate
Description
MENT, short for methylnortestosterone (acetate), is a synthetic anabolic steroid derived from nandrolone. This agent is also called trestolone acetate, although not as commonly. The trivial name methylnortestosterone is vague, and can also be applied to other steroids. In this
case the “methyl” in the name, which is commonly associated with C-17 alpha alkylated androgens like methyltestosterone, methandrostenolone, or oxymetholone, is referring to a modification at C-7. This gives MENT a considerably different appearance than 17-methylnoretestosterone (Orgasteron). Of most obvious significance its method of use. Although perhaps possessing a moderate level of oral bioavailability, this nandrolone derivative was not designed for oral administration. It is much more effective when administered to the body directly, by injection, implant, or transdermal gel. In character, MENT is a strongly anabolic
and estrogenic properties.
General steroid potency is usually increased with 7-methylation, a trait well illustrated with MENT. When methylation increases steroid potency it is usually due to one or a couple of things, most notably increased resistance to hepatic metabolism (breakdown) or reduced
affinity for constrictive binding proteins. In the case of MENT, we see a steroid with relatively fast metabolic breakdown, but no binding to SHBG (Sex Hormone-Binding Globulin). Therefore, reduced binding to serum
proteins seems to be partly responsible for making MENT a more potent steroid. When assayed in 1963, scientists reported an anabolic effect that was between 3.5 and 23
times greater than testosterone, while being only 3-6 times more androgenic.2 3 When investigated in primates in 1998, it was shown to have 10 times more anabolic potency than testosterone, with only 2 times the stimulatory action on the prostate. Its relative androgen
receptor binding affinity was investigated a year later, and provided further explanation for the strong anabolic effect of this steroid. Here, MENT was shown to bind the androgen receptor more strongly than testosterone, nandrolone, or dihydrotestosterone.